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Audio overload nsf7/4/2023 ![]() ![]() ![]() All media in the gallery are intended for personal, educational and nonprofit/non-commercial use only. Images and other media in the National Science Foundation Multimedia Gallery are available for use in print and electronic material by NSF employees, members of the media, university staff, teachers and the general public. This image accompanied NSF press release, "Autoimmune Overload May Damage HIV-Infected Brain."Ĭredit: Zina Deretsky, National Science Foundation The tool was developed with the support of an NSF Small Business Innovation Research award. One of the critical tools behind the discovery is HIVBase, a genetic data-storage and -analysis tool with which the researchers tracked the rapidly evolving viruses. The findings could lead to new treatments that target HIV-infected white blood cells, perhaps one day countering the brain wasting that will affect as many as 15 percent of the nearly 40 million people around the world who are infected with the virus. The associated overcrowding and inflammation appear to cause the dementia. National Science Foundation-supported researchers showed that HIV in the temporal lobe mutates at a rate 100 times faster than in other parts of the body, triggering white blood cells to continually swarm to attack the infection. Researchers now believe that the inflammation from this process may lead to HIV-related dementia. This illustration depicts white blood cells swarming to attack HIV in the brain. ApAutoimmune Overload May Damage HIV-Infected Brain
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